Gastritis describes a group of conditions with one thing in common: inflammation of the lining of the stomach. The inflammation of gastritis is often the result of infection with the same bacterium that causes most stomach ulcers. However, other factors — such as injury, regular use of certain pain relievers or drinking too much alcohol — also can contribute to gastritis.
Gastritis may occur suddenly (acute gastritis) or it can occur slowly over time (chronic gastritis). In some cases, gastritis can lead to ulcers and an increased risk of stomach cancer. For most people, however, gastritis isn't serious and improves quickly with treatment.
Symptoms
- A gnawing or burning ache or pain (indigestion) in your upper abdomen that may become either worse or better with eating
- Nausea
- Vomiting
- A feeling of fullness in your upper abdomen after eating
Gastritis doesn't always cause signs and symptoms.
When to see a doctor
Nearly everyone has experienced a bout of indigestion and stomach irritation. Most cases of indigestion are short-lived and don't require medical care. But if you experience signs and symptoms of gastritis consistently for a week or longer, see your doctor. And be sure to tell your doctor if you experience stomach problems after taking any prescription or over-the-counter drugs, especially aspirin or other pain relievers.
Nearly everyone has experienced a bout of indigestion and stomach irritation. Most cases of indigestion are short-lived and don't require medical care. But if you experience signs and symptoms of gastritis consistently for a week or longer, see your doctor. And be sure to tell your doctor if you experience stomach problems after taking any prescription or over-the-counter drugs, especially aspirin or other pain relievers.
If you are vomiting blood, you have blood in your stools or your stool appears black, see your doctor right away to determine the cause.
Causes
Gastritis usually develops when your stomach's protective layer becomes weakened or damaged. A mucus-lined barrier protects the wall of your stomach from the acids that help digest your food. Weaknesses in the barrier allow your digestive juices to damage and inflame your stomach lining. A number of diseases and conditions can make your stomach's protective layer vulnerable to damage and increase your risk of gastritis.
Gastritis can occur suddenly or develop over weeks and months:
- Acute gastritis is stomach inflammation that develops quickly and lasts for a short period of time.
- Chronic gastritis develops gradually and may last for an extended period of time.
Risk factors
Factors that increase your risk of gastritis include:
- Bacterial infection. People infected with Helicobacter pylori can experience gastritis — most commonly chronic gastritis. Half the world's population is thought to be infected with this bacterium, which is thought to pass from person to person. But the majority of those infected don't experience any complications of H. pylori infection. In some people, H. pylori may break down the stomach's inner protective coating, causing changes in the stomach's lining. The reason why some people experience complications from H. pylori infection, such as gastritis and ulcers, and others don't isn't clear. However, doctors believe vulnerability to the bacterium could be inherited or it could be caused by lifestyle choices, such as smoking and high stress levels.
- Regular use of pain relievers. Common pain relievers, such as aspirin, ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Anaprox), can cause both acute gastritis and chronic gastritis. Using these pain relievers regularly or taking too much of these drugs may reduce a key substance that helps preserve the protective lining of your stomach. Stomach problems are less likely to develop if you take pain relievers only occasionally.
- Older age. Older adults have an increased risk of gastritis because the stomach lining tends to thin with age and because older adults are more likely to have H. pylori infection or autoimmune disorders than younger people are.
- Excessive alcohol use. Alcohol can irritate and erode your stomach lining, which makes your stomach more vulnerable to digestive juices. Excessive alcohol use is more likely to cause acute gastritis.
- Stress. Severe stress due to major surgery, injury, burns or severe infections can cause acute gastritis.
- Bile reflux disease. Bile — a substance that helps you digest fats — is produced in your liver and stored in your gallbladder. When it's released from the gallbladder, bile travels to your small intestine through a series of thin tubes. Normally, a ring-like sphincter muscle (pyloric valve) prevents bile from flowing into your stomach from your small intestine. But if this valve doesn't work properly, or if it has been surgically removed, bile can flow into your stomach, leading to gastritis.
- Your own body attacking cells in your stomach. Called autoimmune gastritis, this type of gastritis occurs when your body attacks the cells that make up your stomach lining. This produces a reaction by your immune system that can wear away at your stomach's protective barrier. Autoimmune gastritis is more common in people with other autoimmune disorders, including Hashimoto's disease and type 1 diabetes. Autoimmune gastritis can also be associated with vitamin B-12 deficiency.
- Other diseases and conditions. Gastritis may be associated with other medical conditions, including HIV/AIDS, Crohn's disease and parasitic infections.
Complications
Left untreated, gastritis may lead to stomach ulcers and stomach bleeding. Some forms of chronic gastritis may increase your risk of stomach cancer, especially if you have extensive thinning of the stomach lining and changes in the lining's cells.
Tell your doctor if your signs and symptoms aren't improving despite treatment for gastritis.
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